SANOFI WINTHROP INDUSTRIE
Contents
Leflunomide
Indication
Rheumatoid arthritis, Psoriatic arthritis
Instruction
May be taken with or without food.
Drug interaction
Cholestyramine and activated charcoal may decrease plasma concentration of active metabolite. Concurrent use of methotrexate and other hepatotoxic drugs may increase the risk of hepatotoxicity. Rifampicin increases serum levels of the active metabolite. Potentially Fatal: May enhance the adverse effects of live vaccines.
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